Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 12/20 | 0.50 |
| ▸ | CNR1 | P21554 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268705 | 0.83 | PPARA (0.62) | PTGESALOX5PPARGCTRCPPARA | |
| SCHEMBL31442547 | 0.82 | PTGS2 (0.63) | PTGS2CNR2CNR1CYP3A4 | |
| SCHEMBL5386932 | 0.82 | CNR1 (0.60) | PTGS2CNR2CNR1 | |
| SCHEMBL5696326 | 0.81 | PPARA (0.70) | PTGESALOX5PPARGCTRCPPARA | |
| SCHEMBL15199289 | 0.81 | PPARA (0.70) | PTGESALOX5PPARGCTRCPPARA | |
| SCHEMBL27689995 | 0.81 | PPARA (0.70) | PTGESALOX5PPARGCTRCPPARA | |
| SCHEMBL31442578 | 0.81 | PTGS2 (0.61) | PTGS2CNR2CNR1CYP3A4 | |
| SCHEMBL5275697 | 0.80 | CTRC (0.55) | PTGESALOX5PPARGCYP3A4CTRC | |
| SCHEMBL5270700 | 0.80 | ALOX5 (0.55) | PTGESALOX5PPARGCNR2CNR1 | |
| SCHEMBL4264526 | 0.79 | PTGS2 (0.67) | PTGS2CNR2CNR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846364-A1 | NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | Universita' Degli Studi di Siena (IT) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006080040-A1 | NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2006-08-03 | — | — | WO | disclosed |