Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.67 |
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | CCR9 | P51686 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198698 | 0.88 | CCR2 (0.71) | CCR2CCR9 | |
| SCHEMBL3578136 | 0.88 | PPARG (0.54) | CCR2PPARG | |
| SCHEMBL3956751 | 0.88 | CCR2 (0.84) | CCR2CCR9 | |
| SCHEMBL6308312 | 0.86 | CCR9 (0.55) | CCR2PPARGCCR9 | |
| SCHEMBL9536869 | 0.85 | CCR2 (0.76) | CCR2CCR9 | |
| SCHEMBL6300893 | 0.84 | CCR2 (0.63) | CCR2PPARGCCR9 | |
| SCHEMBL3198946 | 0.84 | CCR2 (0.71) | CCR2PPARGCCR9 | |
| SCHEMBL6599972 | 0.84 | PPARG (0.68) | CCR2PPARGCCR9 | |
| SCHEMBL940279 | 0.84 | CCR2 (0.59) | CCR2PPARGCCR9 | |
| SCHEMBL3718258 | 0.84 | CCR2 (0.67) | CCR2PPARGCCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1776340-A1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sanofi-Aventis (FR) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006024776-A1 | N(1 H-INDOLYL)-1 H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI-AVENTIS (FR) | 2006-03-09 | — | — | WO | disclosed |