SCHEMBL4655435

SCHEMBL4655435

CCCCCC(C)(C)c1ccc(C(=O)c2ccc(O)cc2O)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.54
CNR1 P21554 17/20 0.52
CNR2 P34972 17/20 0.52
KDM4E B2RXH2 1/20 0.51
HSP90AB1 P08238 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317179 0.85 CNR1 (0.56) CNR1CNR2
SCHEMBL1129199 0.83 CNR1 (0.58) CNR1CNR2
SCHEMBL4654424 0.82 HTT (0.51) HTTKDM4EHSP90AB1
SCHEMBL4655434 0.80 SHBG (0.54) HTTKDM4EHSP90AB1
SCHEMBL420915 0.78 CNR1 (0.64) CNR1CNR2
SCHEMBL5479223 0.78 ALDH1A1 (0.52) HTTHSP90AB1
SCHEMBL5712297 0.77 CNR2 (0.52) CNR1CNR2
SCHEMBL9493133 0.77 CNR1 (0.51) CNR1CNR2
SCHEMBL1110468 0.76 KAT8 (0.55) CNR1CNR2
SCHEMBL11324559 0.76 CNR1 (0.53) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746822-B1 PLASTIC LENS HOYA CORP (JP) 2016-01-20 EP disclosed
US-8895661-B2 Plastic lens HOYA CORPORATION (JP) 2014-11-25 US disclosed
EP-2746822-A1 PLASTIC LENS HOYA CORPORATION (JP) 2014-06-25 EP disclosed
EP-1505412-B1 Plastic lens and process for producing the lens HOYA CORP (JP) 2008-11-05 EP disclosed
US-20050046967-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-03-03 US disclosed
EP-1505412-A1 Plastic lens and process for producing the lens HOYA CORPORATION (JP) 2005-02-09 EP disclosed