Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317178 | 0.83 | SHBG (0.50) | SHBGMEN1KMT2AUSP2GAA | |
| SCHEMBL5479223 | 0.82 | ALDH1A1 (0.52) | HSP90AB1MEN1KMT2AUSP2GAA | |
| SCHEMBL4655435 | 0.80 | HTT (0.54) | HSP90AB1HTTKDM4E | |
| SCHEMBL4654422 | 0.79 | NPC1 (0.51) | HSP90AB1MEN1KMT2AUSP2GAA | |
| SCHEMBL29357695 | 0.76 | CES2 (0.73) | SHBGHSP90AB1MEN1KMT2AUSP2 | |
| SCHEMBL39507 | 0.76 | CES2 (0.73) | SHBGHSP90AB1MEN1KMT2AUSP2 | |
| SCHEMBL340386 | 0.75 | SHBG (0.61) | SHBGMEN1KMT2AUSP2GAA | |
| SCHEMBL68434 | 0.75 | SHBG (0.61) | SHBGMEN1KMT2AUSP2GAA | |
| SCHEMBL28750425 | 0.75 | TDP1 (0.59) | HSP90AB1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL29457570 | 0.75 | SHBG (0.61) | SHBGMEN1KMT2AUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746822-B1 | PLASTIC LENS | HOYA CORP (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-8895661-B2 | Plastic lens | HOYA CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2746822-A1 | PLASTIC LENS | HOYA CORPORATION (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-1505412-B1 | Plastic lens and process for producing the lens | HOYA CORP (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20050046967-A1 | Plastic lens and process for preparing the lens | HOYA CORPORATION (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1505412-A1 | Plastic lens and process for producing the lens | HOYA CORPORATION (JP) | 2005-02-09 | — | — | EP | disclosed |