SCHEMBL4655458

SCHEMBL4655458

Oc1c(Cl)cccc1Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.58
ALDH1A1 P00352 4/20 0.50
NPSR1 Q6W5P4 2/20 0.50
LMNA P02545 2/20 0.49
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPK8 P45983 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
FABP3 P05413 1/20 0.43
FABP4 P15090 1/20 0.43
ACLY P53396 1/20 0.43
LTA4H P09960 2/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
CTNNB1 P35222 1/20 0.43
TSHR P16473 1/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454010 0.85 AKR1B1 (0.43) DPP4ALDH1A1LMNAMAPTTSHR
SCHEMBL2916124 0.85 LTA4H (0.52) DPP4ALDH1A1LMNAL3MBTL1LTA4H
SCHEMBL20787024 0.83 CXCL8 (0.49) DPP4ALDH1A1LMNAHPGD
SCHEMBL396882 0.81 ALDH1A1 (0.52) DPP4ALDH1A1LMNAMAPTTDP1
SCHEMBL3790160 0.81 DPP4 (0.62) DPP4ALDH1A1NPSR1LMNAPOLB
SCHEMBL3667279 0.79 DPP4 (0.61) DPP4ALDH1A1NPSR1LMNAPOLB
Ammonia Solution, Strong SCHEMBL4267774 0.79 DPP4 (0.60) DPP4ALDH1A1NPSR1LMNAPOLB
SCHEMBL4239846 0.78 ALDH1A1 (0.45) DPP4ALDH1A1NPSR1TDP1ACLY
SCHEMBL9768120 0.78 LTA4H (0.55) ALDH1A1LMNALTA4HNR1H2BAX
SCHEMBL10930169 0.78 RHEB (0.50) ALDH1A1NPSR1MAPTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449909-B1 Highly deodorizing cleansing agents for washing clothing articles DELLA CUNA LAURA (IT) 2008-12-03 EP claimed
WO-2001079349-A1 UREA MOULDING COMPOUNDS WITH ANTISEPTIC ACTIVITY PERSTORP CHEMITEC S.P.A. (IT) 2001-10-25 WO claimed
US-20140113093-A1 Polymers with reduced estrogenic activity SOLVAY SPECIALITY POLYMERS USA, LLC (US) 2014-04-24 US disclosed
WO-2012160172-A1 POLYMERS WITH REDUCED ESTROGENIC ACTIVITY SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2012-11-29 WO disclosed
EP-1927342-A2 Hygienic and cosmetic compositions for treating sensitive skins Betafarma S.p.A. (IT) 2008-06-04 EP disclosed
US-20080118451-A1 Hygienic and cosmetic compositions for treating sensitive skins BETAFARMA S.P.A (IT) 2008-05-22 US disclosed
US-3960868-A Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed