Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.73 |
| ▸ | THRB | P10828 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4658176 | 0.99 | TDP1 (0.76) | TDP1MAPK1THRBMEN1KMT2A | |
| Perchlorate SCHEMBL4658062 | 0.95 | TDP1 (0.66) | TDP1MAPK1THRBMEN1KMT2A | |
| Perchlorate SCHEMBL4655655 | 0.94 | TDP1 (0.64) | TDP1MAPK1THRBMEN1KMT2A | |
| Hexamethyl Pararosaniline SCHEMBL94116 | 0.87 | TDP1 (0.96) | TDP1MAPK1THRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4657185 | 0.86 | THRB (0.54) | TDP1MAPK1THRBMEN1KMT2A | |
| Hexamethyl Pararosaniline SCHEMBL9171 | 0.85 | TDP1 (1.00) | TDP1MAPK1THRBMEN1KMT2A | |
| SCHEMBL14310873 | 0.81 | TDP1 (0.84) | TDP1MAPK1THRBMEN1KMT2A | |
| Brilliant Green SCHEMBL171205 | 0.81 | TDP1 (0.84) | TDP1MAPK1THRBMEN1KMT2A | |
| SCHEMBL171347 | 0.80 | MAPK1 (0.82) | TDP1MAPK1THRBMEN1KMT2A | |
| Brilliant Green SCHEMBL28216 | 0.80 | TDP1 (0.88) | TDP1MAPK1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435227-B1 | Composition for the dyeing of keratinous fibres comprising a direct dye of the monoheteroyldiarylmethane type or a leuco precursor thereof and a dyeing process using it | OREAL (FR) | 2008-12-03 | — | — | EP | claimed |
| EP-1435227-A1 | Composition for the dyeing of keratinous fibres comprising a direct colourant ofthe monoheteroyldiarylmethane type of a leuco precursor thereof and a dyeing process using it | L'OREAL (FR) | 2004-07-07 | — | — | EP | claimed |
| EP-1435227-B1 | Composition for the dyeing of keratinous fibres comprising a direct dye of the monoheteroyldiarylmethane type or a leuco precursor thereof and a dyeing process using it | OREAL (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1435227-A1 | Composition for the dyeing of keratinous fibres comprising a direct colourant ofthe monoheteroyldiarylmethane type of a leuco precursor thereof and a dyeing process using it | L'OREAL (FR) | 2004-07-07 | — | — | EP | disclosed |