SCHEMBL4656127

SCHEMBL4656127

CCCCn1c(=O)cc(CN)[nH]c1=S

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
ALDH1A1 P00352 6/20 0.40
TSHR P16473 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPK10 P53779 1/20 0.40
HTT P42858 2/20 0.39
HSD17B10 Q99714 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ATM Q13315 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
ADRA2A P08913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9420352 0.80 MAPT (0.45) MAPTALDH1A1TSHRKDM4EMAPK10
SCHEMBL9765877 0.74 SMN1; SMN2 (0.42) MAPTALDH1A1TSHRKDM4EHSD17B10
SCHEMBL9420328 0.74 MAPK10 (0.50) MAPTALDH1A1TSHRKDM4EMAPK10
SCHEMBL9420340 0.74 MAPK10 (0.50) MAPTALDH1A1TSHRKDM4EMAPK10
SCHEMBL9420350 0.74 MAPK10 (0.50) MAPTALDH1A1TSHRKDM4EMAPK10
SCHEMBL9420342 0.74 MAPK10 (0.50) MAPTALDH1A1TSHRKDM4EMAPK10
SCHEMBL9414222 0.70 TSHR (0.52) MAPTALDH1A1TSHRKDM4EMAPK10
SCHEMBL1945200 0.68 TSHR (0.54) MAPTALDH1A1TSHRKDM4ELMNA
SCHEMBL3243411 0.68 ALDH1A1 (0.41) MAPTALDH1A1TSHRKDM4EATM
SCHEMBL10616922 0.68 MAPT (0.43) MAPTALDH1A1KDM4EHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996649-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE Baerlocher GmbH (DE) 2008-12-03 EP disclosed
WO-2007104379-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE BAERLOCHER GMBH (DE) 2007-09-20 WO disclosed