SCHEMBL4656144

SCHEMBL4656144

COc1ccc(C(c2ccc(O)cc2)c2ccc(OC)cc2O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.54
TYR P14679 1/20 0.54
ACHE P22303 1/20 0.54
ESR2 Q92731 2/20 0.50
LTA4H P09960 1/20 0.50
CYP3A4 P08684 2/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
PPARG P37231 1/20 0.47
KMT2A Q03164 1/20 0.47
APP P05067 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
CYP2C19 P33261 1/20 0.46
MCL1 Q07820 1/20 0.46
CALM1 P0DP23 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758750 0.91 TYR (0.58) BCHETYRACHECYP3A4MAPT
SCHEMBL5584056 0.90 TYR (0.55) BCHETYRACHECYP3A4MAPT
SCHEMBL25446759 0.83 ESR2 (0.64) ESR2LTA4HCYP3A4MAPTMEN1
SCHEMBL13528449 0.83 ESR2 (0.64) ESR2LTA4HCYP3A4MAPTMEN1
SCHEMBL17356547 0.83 ESR2 (0.64) ESR2LTA4HCYP3A4MAPTMEN1
SCHEMBL50738 0.83 TYR (0.54) BCHETYRACHECYP3A4MAPT
SCHEMBL5028467 0.82 TYR (0.54) BCHETYRACHECYP3A4MAPT
SCHEMBL4000430 0.81 TYR (0.55) BCHETYRACHEESR2LTA4H
SCHEMBL9226079 0.80 CA1 (0.54) BCHETYRACHECYP3A4MAPT
SCHEMBL26696412 0.80 BCHE (0.42) BCHETYRACHEESR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 BCHE 588/4885TYR 1545/4885ACHE 1054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.