Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.70 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.70 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.70 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.67 |
| ▸ | ESR1 | P03372 | 8/20 | 0.67 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylamine SCHEMBL3581231 | 0.92 | FGFR1 (0.63) | FGFR1FGFR2FGFR4FGFR3ESR2 | |
| SCHEMBL4656306 | 0.89 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3ESR2 | |
| SCHEMBL3578768 | 0.84 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3ESR2 | |
| SCHEMBL147279 | 0.83 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL4656549 | 0.82 | FGFR1 (0.48) | FGFR1FGFR2FGFR4FGFR3ESR2 | |
| SCHEMBL3570952 | 0.81 | PPARG (0.74) | FGFR1FGFR2FGFR4FGFR3ESR2 | |
| SCHEMBL3922937 | 0.80 | ESR2 (1.00) | ESR2ESR1MAOAUGT1A1MAOB | |
| SCHEMBL5611249 | 0.79 | FGFR1 (0.62) | FGFR1FGFR2FGFR4FGFR3ESR2 | |
| SCHEMBL4658483 | 0.79 | PPARG (0.73) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL8215899 | 0.79 | ESR2 (0.69) | ESR2ESR1MAOAUGT1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745439-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-29 | — | — | US | disclosed |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | JEIL PHARM. CO., LTD. (KR) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | INSR, GPR119, PPARA | FGFR1 41/4885FGFR2 124/4885FGFR4 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.