Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.73 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.62 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.62 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.62 |
| ▸ | SRC | P12931 | 4/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138210 | 0.84 | PPARG (0.57) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL3572575 | 0.84 | PPARG (1.00) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL6555666 | 0.80 | PPARG (0.76) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL3575957 | 0.79 | FGFR1 (0.70) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL4656306 | 0.79 | FGFR1 (0.68) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL3577919 | 0.78 | PPARG (0.77) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL147279 | 0.78 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL4659855 | 0.77 | PPARG (0.84) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL4659852 | 0.77 | PPARG (0.84) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| Isopropylamine SCHEMBL3581231 | 0.75 | FGFR1 (0.63) | PPARGFGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756036-A4 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-04-16 | — | — | EP | disclosed |
| EP-1756036-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100297-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |