Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.52 |
| ▸ | KDM4A | O75164 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.52 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14893946 | 1.00 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL16187177 | 1.00 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL598016 | 0.84 | LCK (0.56) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL11536608 | 0.82 | LCK (0.59) | FOLH1ALDH1A1TSHRLCKPPARD | |
| SCHEMBL2776377 | 0.82 | ALDH1A1 (0.61) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL5965619 | 0.82 | ALDH1A1 (0.61) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL11534282 | 0.80 | PPARD (0.63) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL11532880 | 0.80 | PPARD (0.63) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL11539998 | 0.80 | PPARD (0.63) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL11535630 | 0.80 | PPARD (0.63) | ALDH1A1TSHRLCKPPARDZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146528-B | Amino-functionalized metal organic framework material and preparation method and application thereof | 淮阴师范学院 | 2025-01-28 | — | — | CN | claimed |
| US-12012378-B2 | Method for synthesizing 2-bromoglutaric acid diesters | GUERBET (FR) | 2024-06-18 | — | — | US | claimed |
| CN-118146528-A | Amino-functionalized metal organic framework material and preparation method and application thereof | 淮阴师范学院 | 2024-06-07 | — | — | CN | claimed |
| CN-117682952-A | Method for synthesizing 2-bromo-glutarate diester | 法国加栢 | 2024-03-12 | — | — | CN | claimed |
| CN-115768741-B | Method for synthesizing 2-bromo-glutarate diester | 法国加栢 | 2023-12-22 | — | — | CN | claimed |
| US-20230303477-A1 | METHOD FOR SYNTHESIZING 2-BROMOGLUTARIC ACID DIESTERS | GUERBET (FR) | 2023-09-28 | — | — | US | claimed |
| US-20230303725-A1 | ALGINATE-BASED POLYMERS AND PRODUCTS, AND THEIR MANUFACTURE | Keel Labs, Inc. (US) | 2023-09-28 | — | — | US | claimed |
| EP-4143153-B1 | METHOD FOR SYNTHESISING DIESTERS OF 2-BROMO GLUTARIC ACID | GUERBET SA (FR) | 2023-09-20 | — | — | EP | claimed |
| EP-4199749-A1 | ALGINATE-BASED POLYMERS AND PRODUCTS, AND THEIR MANUFACTURE | Keel Labs, Inc. (US) | 2023-06-28 | — | — | EP | claimed |
| CN-115884779-A | Alginate-based polymers and products and their manufacture | 吉尔实验室股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| EP-4143153-A1 | METHOD FOR SYNTHESISING 2-BROMOGLUTARIC ACID DIESTERS | Guerbet (FR) | 2023-03-08 | — | — | EP | claimed |
| CN-115768741-A | Method for synthesizing 2-bromoglutaric acid diester | 法国加栢 | 2023-03-07 | — | — | CN | claimed |
| EP-3902800-B1 | COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED FROM A DIASTEREOISOMERICALLY ENRICHED PCTA AND PREPARATION AND PURIFICATION PROCESS | GUERBET SA (FR) | 2022-09-07 | — | — | EP | claimed |
| EP-3902799-B1 | COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED OF A DIASTEREOISOMERICALLY ENRICHED PCTA AND SYNTHESIS METHOD | GUERBET SA (FR) | 2022-07-27 | — | — | EP | claimed |
| WO-2022040044-A1 | ALGINATE-BASED POLYMERS AND PRODUCTS, AND THEIR MANUFACTURE | ALGIKNIT INC. (US) | 2022-02-24 | — | — | WO | claimed |
| EP-3902799-A1 | COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED OF A DIASTEREOISOMERICALLY ENRICHED PCTA AND SYNTHESIS METHOD | Guerbet (FR) | 2021-11-03 | — | — | EP | claimed |
| WO-2020148431-A1 | COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED OF A DIASTEREOISOMERICALLY ENRICHED PCTA AND SYNTHESIS METHOD | GUERBET (FR) | 2020-07-23 | — | — | WO | claimed |
| CN-102516741-A | Method of reducing the styrene content of a poly(arylene ether)/polystyrene blend, and articles comprising the resulting thermoplastic resin | SABIC INNOVATIVE PLASTICS IP | 2012-06-27 | — | — | CN | claimed |
| CN-101313022-A | Polymer blend method, composition, and article | GEN ELECTRIC (US) | 2008-11-26 | — | — | CN | claimed |
| CN-101287799-A | Method of reducing the styrene content of poly (arylene ether)/polystyrene blends, and articles comprising the resulting thermoplastic resins | GEN ELECTRIC (US) | 2008-10-15 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12012378-B2 | Method for synthesizing 2-bromoglutaric acid diesters | OGDH, GCDH, HSD17B12 | TET2 677/4885KDM4A 2562/4885KDM4C 1844/4885 |
| US-20230303477-A1 | METHOD FOR SYNTHESIZING 2-BROMOGLUTARIC ACID DIESTERS | OGDH, GCDH, HSD17B12 | TET2 677/4885KDM4A 2562/4885KDM4C 1844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.