SCHEMBL465647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL888056	0.78	TAAR1 (0.55)	TAAR1IDO1MAOBALDH1A1PYCR1
	SCHEMBL91061	0.73	TAAR1 (0.54)	TAAR1IDO1MAOBALDH1A1PYCR1
	SCHEMBL934227	0.72	TAAR1 (0.73)	TAAR1IDO1MAOBALDH1A1KDM4E
	SCHEMBL2096666	0.72	SRD5A2 (0.59)	TAAR1IDO1MAOBALDH1A1KDM4E
	Ammonia Solution, Strong SCHEMBL266277	0.71	TAAR1 (0.52)	TAAR1IDO1MAOBALDH1A1PYCR1
	SCHEMBL465784	0.71	ALDH1A1 (0.45)	TAAR1IDO1MAOBALDH1A1PYCR1
	SCHEMBL63468	0.71	ALDH1A1 (0.67)	TAAR1IDO1ALDH1A1KIF11TSHR
	SCHEMBL28906098	0.70	IDO1 (0.48)	TAAR1IDO1ALDH1A1
	SCHEMBL10544537	0.70	TAAR1 (0.56)	TAAR1IDO1MAOBALDH1A1KDM4E
	SCHEMBL28701927	0.70	TAAR1 (0.56)	TAAR1IDO1MAOBALDH1A1PYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.