Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572176 | 0.97 | ESR1 (0.50) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 | |
| SCHEMBL4656551 | 0.87 | PPARG (0.45) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3575957 | 0.82 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 | |
| SCHEMBL4823811 | 0.79 | PPARG (0.68) | ESR1ESR2NPC1RAB9A | |
| SCHEMBL3577620 | 0.76 | PPARG (0.62) | ALDH1A1MEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL4656306 | 0.76 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3ESR1 | |
| Isopropylamine SCHEMBL3581231 | 0.75 | FGFR1 (0.63) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 | |
| SCHEMBL3574590 | 0.72 | PPARG (0.73) | NPC1RAB9AKDM4ECNR1CNR2 | |
| SCHEMBL3578768 | 0.71 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3ESR1 | |
| SCHEMBL147279 | 0.68 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756036-A4 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-04-16 | — | — | EP | disclosed |
| EP-1756036-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100297-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |