Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656788 | 1.00 | NR3C1 (0.32) | NR3C1NR3C2KMT2ACTSSPGR | |
| SCHEMBL4655524 | 0.85 | — | — | |
| SCHEMBL4655526 | 0.85 | — | — | |
| SCHEMBL4597487 | 0.81 | CTSS (0.34) | KMT2ACTSS | |
| SCHEMBL5920505 | 0.81 | CTSS (0.34) | KMT2ACTSS | |
| SCHEMBL4597490 | 0.81 | CTSS (0.34) | KMT2ACTSS | |
| SCHEMBL3755093 | 0.80 | CTSS (0.36) | KMT2ACTSS | |
| SCHEMBL3755099 | 0.80 | CTSS (0.36) | KMT2ACTSS | |
| SCHEMBL3755089 | 0.80 | CTSS (0.36) | KMT2ACTSS | |
| SCHEMBL4584481 | 0.76 | ALDH1A1 (0.49) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994005-A1 | TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007104582-A1 | TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-20 | — | — | WO | disclosed |