Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657812 | 0.88 | TDP1 (0.49) | ALDH1A1HPGDTSHRPOLBCYP2C19 | |
| SCHEMBL6680911 | 0.82 | POLB (0.60) | ALDH1A1HPGDTSHRPOLBCYP2C19 | |
| SCHEMBL4657814 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRPOLBMEN1 | |
| SCHEMBL28123482 | 0.79 | POLB (0.54) | ALDH1A1HPGDTSHRPOLBCYP2C19 | |
| SCHEMBL10652363 | 0.79 | SLC6A2 (0.54) | ALDH1A1HPGDTSHRPOLBCYP2C19 | |
| SCHEMBL10047204 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDTSHRPOLBCYP2C19 | |
| SCHEMBL2214742 | 0.76 | ALDH1A1 (0.67) | ALDH1A1HPGDTSHRPOLBCYP2C19 | |
| SCHEMBL3202573 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL4658040 | 0.75 | POLB (0.53) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL8334178 | 0.75 | ALDH1A1 (0.71) | ALDH1A1HPGDTSHRPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1295864-B1 | PROCESS FOR PREPARATION OF 1,5-DIAMINONAPHTHALENES | MITSUI CHEMICALS POLYURETHANES (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6737548-B2 | REACTING AN ORTHO-ALKYLNITROBENZENE WITH VINYL COMPOUND IN PRESENCE OF A BASE TO PRODUCE AN INTERMEDIATE, CYCLIZING THE INTERMEDIATE TO FORM 5-NITRO-1-TETRALONE COMPOUND, THEN REACTING WITH AMINE TO PRODUCE DIAMINONAPHTHALENE COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 2004-05-18 | — | — | US | disclosed |
| US-20030176722-A1 | Process for preparation of 1,5-diaminonaphthalenes | MITSUI CHEMICALS POLYURETHANES, INC. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1295864-A1 | PROCESS FOR PREPARATION OF 1,5-DIAMINONAPHTHALENES | Mitsui Chemicals, Inc. (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176722-A1 | Process for preparation of 1,5-diaminonaphthalenes | NOX5, NOX1, DPYD | ALDH1A1 159/4885HPGD 532/4885TSHR 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.