SCHEMBL4657272

SCHEMBL4657272

CCCCc1nc(Cl)c(C)c(CO)c1C(C)(CC)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 5/20 0.36
AGTR2 P50052 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611575 0.84 AGTR1 (0.42) AGTR1
SCHEMBL30604711 0.84 AGTR1 (0.42) AGTR1
SCHEMBL4669528 0.76 AGTR1 (0.37) AGTR1
SCHEMBL9846036 0.74 GP6 (0.41)
SCHEMBL9846014 0.70
SCHEMBL9846060 0.70
SCHEMBL9845997 0.69
SCHEMBL9846023 0.69
SCHEMBL9846044 0.69
SCHEMBL9709728 0.69 PDE4A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877373-A2 BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS Microbia, Inc. (US) 2008-01-16 EP disclosed
WO-2006121861-A2 BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS MICROBIA, INC. (US) 2006-11-16 WO disclosed