Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611575 | 0.90 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL30604711 | 0.90 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9543200 | 0.81 | PDE4A (0.39) | AGTR1PSMB5 | |
| SCHEMBL9268311 | 0.81 | PSMB5 (0.37) | PSMB5 | |
| SCHEMBL9276477 | 0.78 | CCR2 (0.39) | — | |
| SCHEMBL9308858 | 0.77 | — | — | |
| SCHEMBL9846036 | 0.77 | GP6 (0.41) | — | |
| SCHEMBL9539419 | 0.77 | — | — | |
| SCHEMBL9709728 | 0.77 | PDE4A (0.42) | — | |
| SCHEMBL4657272 | 0.76 | AGTR1 (0.36) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996218-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | Ironwood Pharmaceuticals, Inc. (US) | 2008-12-03 | — | — | EP | disclosed |
| EP-1940441-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | Microbia, Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007101161-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007022531-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | MICROBIA INC (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007022531-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006102069-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND GASTROINTESTINAL DISORDERS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |