SCHEMBL4657447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4658834	0.84	MAOA (0.33)	TAAR1ALDH1A1
	SCHEMBL4656299	0.83	ATM (0.41)	ATMCYP1A2CYP1A1CYP1B1SLC6A2
	SCHEMBL4657451	0.82	TAAR1 (0.39)	TAAR1ALDH1A1
	SCHEMBL5711847	0.82	FDPS (0.35)	CYP1A2ALDH1A1CYP2C9CYP2C19CYP2D6
	SCHEMBL4658860	0.82	SLC6A4 (0.39)	SLC6A2TAAR1ALDH1A1EPHX2LMNA
	SCHEMBL4723541	0.82	MAOB (0.33)	CYP1A2CYP1A1CYP1B1TAAR1ALDH1A1
	SCHEMBL4657169	0.82	ESR1 (0.33)	ATMCYP1A2TAAR1ALDH1A1
	SCHEMBL5001946	0.82	CYP2A6 (0.41)	CYP1A2TAAR1ALDH1A1CYP2C9CYP2C19
	SCHEMBL4657566	0.82	LOXL2 (0.41)	SMN1; SMN2NPC1TRPA1
	SCHEMBL4657371	0.82	ESR1 (0.32)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.