Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656984 | 0.94 | NPC1 (0.57) | NPC1RAB9AHDAC1HDAC2HPGD | |
| SCHEMBL4657065 | 0.92 | RAB9A (0.59) | NPC1RAB9AHDAC1HDAC2HPGD | |
| SCHEMBL4658408 | 0.88 | MEN1 (0.51) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL4658142 | 0.87 | RAB9A (0.60) | NPC1RAB9AHDAC1HDAC2KMT2A | |
| SCHEMBL13979548 | 0.86 | HDAC1 (0.56) | NPC1RAB9AHDAC1HDAC2HPGD | |
| SCHEMBL4657080 | 0.85 | RAB9A (0.57) | NPC1RAB9AHDAC1HDAC2KMT2A | |
| SCHEMBL4657708 | 0.84 | RAB9A (0.52) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL4657775 | 0.84 | RAB9A (0.58) | NPC1RAB9AHDAC1HDAC2HPGD | |
| SCHEMBL3866558 | 0.83 | MEN1 (0.52) | NPC1RAB9AHDAC1HDAC2HPGD | |
| SCHEMBL5442668 | 0.83 | LMNA (0.49) | NPC1RAB9AHDAC1HDAC2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391199-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2008-12-10 | — | — | EP | disclosed |
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2007-04-19 | — | — | US | disclosed |
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2007-04-19 | — | — | US | disclosed |
| US-7179817-B2 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-7179817-B2 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-20040224941-A1 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-11 | — | — | US | disclosed |
| EP-1391199-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | EDF1, FFAR1, EDNRA | NPC1 2652/4885RAB9A 4149/4885HDAC1 995/4885 |
| US-20040224941-A1 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | EDF1, FFAR1, VCAM1 | NPC1 1756/4885RAB9A 4064/4885HDAC1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.