SCHEMBL4658355

SCHEMBL4658355

N=NS(=O)(=O)c1ccc(N)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.57
PRSS1 P07477 4/20 0.57
PRSS2 P07478 4/20 0.57
PRSS3 P35030 4/20 0.57
LMNA P02545 2/20 0.57
AGO2 Q9UKV8 2/20 0.57
TSHR P16473 4/20 0.54
HTR6 P50406 2/20 0.54
MPO P05164 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
CA2 P00918 4/20 0.52
CA9 Q16790 4/20 0.52
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA14 Q9ULX7 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
USP2 O75604 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770967 0.76 F2 (0.55) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL7777272 0.76 F2 (0.55) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL12826354 0.76 F2 (0.57) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL18665498 0.76 F2 (0.55) F2PRSS1PRSS2PRSS3CA2
SCHEMBL28574997 0.75 HTR6 (0.50) LMNATSHRHTR6CA2CA9
Sulfaguanidine SCHEMBL1650003 0.73 F2 (1.00) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL1408800 0.72 TSHR (0.64) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL3090434 0.71 F2 (0.52) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL9262293 0.71 F2 (0.57) F2PRSS1PRSS2PRSS3LMNA
Dapsone SCHEMBL1219599 0.71 HTR6 (1.00) LMNAAGO2TSHRHTR6MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4116318-A1 SHAPE MEMORY SILK MATERIALS Tufts University (US) 2023-01-11 EP disclosed
EP-3268381-B1 SHAPE MEMORY SILK MATERIALS UNIV TUFTS (US) 2022-03-02 EP disclosed
US-20210177977-A1 Shape Memory Silk Materials TUFTS UNIVERSITY 2021-06-17 US disclosed
US-10874742-B2 Shape memory silk materials TUFTS UNIVERSITY (US) 2020-12-29 US disclosed
US-20180050109-A1 SHAPE MEMORY SILK MATERIALS TUFTS UNIVERSITY 2018-02-22 US disclosed
EP-3268381-A1 SHAPE MEMORY SILK MATERIALS Tufts University (US) 2018-01-17 EP disclosed
WO-2016145281-A1 SHAPE MEMORY SILK MATERIALS TUFTS UNIVERSITY (US) 2016-09-15 WO disclosed
EP-1221964-B1 ANTIGENIC MODIFICATION OF POLYPEPTIDES UNIV OHIO STATE RES FOUND (US) 2008-12-10 EP disclosed
EP-1864676-A1 Antigenic modification of polypeptides THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2007-12-12 EP disclosed
US-6716428-B1 SYNTHETIC PEPTIDES MIMICK EPITOPE REGIONS OF HORMONES SUCH AS HUMAN CHORIONIC GONADOTROPIN CAN BE CONJUGATED TO CARRIER; CONTRACEPTIVES, ANTICARCINOGENIC AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION 2004-04-06 US disclosed
US-5006334-A Immunogen vaccine; antifertility agent THE OHIO STATE UNIVERSITY (US) 1991-04-09 US disclosed
US-4855285-A Antigenic modification of polypeptides THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1989-08-08 US disclosed
US-4767842-A Antigenic modification of polypeptides THE OHIO STATE UNIVERSITY (US) 1988-08-30 US disclosed
US-4762913-A Antigenic modification of polypeptides THE OHIO STATE UNIVERSITY (US) 1988-08-09 US disclosed
US-4713366-A HORMONE INHIBITORS; ANTIFERTILITY,-CARCINOGENIC AND HYPOTENSIVE AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1987-12-15 US disclosed
US-4691006-A CONTRACEPTIVES, ABORTION, CARCINOMAS, VIRAL PROTEIN RESISTANCE OHIO STATE UNIVERSITY (US) 1987-09-01 US disclosed
US-4526716-A For preparing isoimmunogen for controlling biological action in animal by activating carrier with imide-containing activator, treating with hormone endogenous to the animal THE OHIO STATE UNIVERSITY (US) 1985-07-02 US disclosed
US-4384995-A ACTIVATION WITH A MALEIIMIDE COMPOUND THE OHIO STATE UNIVERSITY (US) 1983-05-24 US disclosed
US-4302386-A HORMONES LINKED TO A GROUP CAUSING IMMUNE RESPONSE THE OHIO STATE UNIVERSITY (US) 1981-11-24 US disclosed
US-4201770-A ANTIFERTILITY AGENTS THE OHIO STATE UNIVERSITY (US) 1980-05-06 US disclosed