Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30495973 | 0.78 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| SCHEMBL31415204 | 0.78 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| SCHEMBL482994 | 0.78 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| SCHEMBL24407 | 0.78 | TSHR (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| Dapsone SCHEMBL5055312 | 0.77 | HTR6 (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| SCHEMBL324893 | 0.77 | HTR6 (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| SCHEMBL10596934 | 0.77 | HTR6 (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| Dapsone SCHEMBL1219599 | 0.77 | HTR6 (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| Dapsone SCHEMBL21428 | 0.77 | HTR6 (1.00) | TSHRALDH1A1NT5ELMNAHTR6 | |
| Sulfuric Acid SCHEMBL10596856 | 0.76 | TSHR (0.95) | TSHRALDH1A1NT5ELMNAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4261217-A9 | COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND | Guangzhou Henovcom Bioscience Co., Ltd. (CN) | 2023-12-27 | — | — | EP | claimed |
| EP-4261217-A1 | COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND | Guangzhou Henovcom Bioscience Co., Ltd. (CN) | 2023-10-18 | — | — | EP | claimed |
| US-10710993-B2 | Benzofuran pyrazole amine kinase inhibitor | Hangzhou REX Pharmaceutical Co., LTD. (CN) | 2020-07-14 | — | — | US | claimed |
| US-20190225600-A1 | BENZOFURAN PYRAZOLE AMINE KINASE INHIBITOR | Hangzhou REX Pharmaceutical Co., LTD. (CN) | 2019-07-25 | — | — | US | claimed |
| EP-3476848-A1 | BENZOFURAN PYRAZOLE AMINE PROTEIN KINASE INHIBITOR | Hangzhou Rex Pharmaceutical Co., Ltd (CN) | 2019-05-01 | — | — | EP | claimed |
| EP-2496628-A1 | METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | BASF SE (DE) | 2012-09-12 | — | — | EP | claimed |
| US-20120208959-A1 | METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | BASF SE (DE) | 2012-08-16 | — | — | US | claimed |
| WO-2011051374-A1 | METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | BASF SE (DE) | 2011-05-05 | — | — | WO | claimed |
| CN-101821243-A | Pyrimidine substituted phenylpropionic acid derivatives and application thereof as PPAR (peroxisome proliferator activated receptor) agonist | CHANGZHEN HOSPITAL SHANGHAI | 2010-09-01 | — | — | CN | claimed |
| EP-1283042-B1 | AQUEOUS LIQUID PREPARATION OF PRANOPROFEN | SENJU PHARMA CO (JP) | 2008-10-08 | — | — | EP | claimed |
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | claimed |
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | claimed |
| US-4876252-A | ADMINISTERING ANTIASTHMATIC OR ANTIALLERGEN | AMERICAN CYANAMID COMPANY (US) | 1989-10-24 | — | — | US | claimed |
| US-4788195-A | TREATING ASTHMA, ALLERGIC DISEASES, INFLAMMATION AND DIABETES IN MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1988-11-29 | — | — | US | claimed |
| EP-0233461-A2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID COMPANY (US) | 1987-08-26 | — | — | EP | claimed |
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | claimed |
| US-4374134-A | Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | claimed |
| US-4061751-A | 6-Substituted 3-nitroimidazo[1,2-b]pyridazine for the control of foot rot and liver lesions in ruminant animals | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | claimed |
| US-4060614-A | 6-Substituted 3-nitroimidazo[1,2-b]pyridazine for the control of hemorrhagic colitis in swine | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | claimed |
| US-3975399-A | PROSTAGLANDIN LIKE ACTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10710993-B2 | Benzofuran pyrazole amine kinase inhibitor | ALK, MAP3K5, ARAF | TSHR 3699/4885ALDH1A1 1248/4885NT5E 3457/4885 |
| US-20190225600-A1 | BENZOFURAN PYRAZOLE AMINE KINASE INHIBITOR | ALK, MAP3K5, ARAF | TSHR 3699/4885ALDH1A1 1248/4885NT5E 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.