Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557827 | 0.89 | PPARG (0.62) | PPARGPTPN1ALDH1A1KDM4EHPGD | |
| SCHEMBL6555686 | 0.86 | FGFR1 (0.59) | PPARGPTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL4658483 | 0.80 | PPARG (0.73) | PPARGPTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL3572575 | 0.76 | PPARG (1.00) | PPARGALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL8196679 | 0.76 | CDK4 (0.50) | PPARGALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL9890648 | 0.75 | HSD17B10 (0.62) | PPARGKDM4ESMN1; SMN2HSD17B10PTGS1 | |
| SCHEMBL7099074 | 0.74 | HSP90AA1 (0.53) | PTPN1ALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL13316091 | 0.71 | PPARG (0.74) | PPARGALDH1A1TDP1 | |
| SCHEMBL13316094 | 0.71 | PPARG (0.74) | PPARGALDH1A1TDP1 | |
| SCHEMBL8235983 | 0.71 | ALKBH3 (0.68) | PPARGPTPN1ALDH1A1SMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958288-B1 | PHOTOCHROMIC NAPHTOPYRANE COLORANTS, METHOD FOR THE PRODUCTION AND USE THEREOF, PHOTOCHROMIC OBJECT | RODENSTOCK GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0987260-B1 | Photochromic spirofluorenopyrans | RODENSTOCK GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6331625-B1 | EYEGLASS LENSES; RAPID COLOR AND BRIGHTNESS ADJUSTMENT | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-12-18 | — | — | US | disclosed |
| US-6225466-B1 | FOR ARTICLES MADE OF SYNTHETIC RESIN MATERIALS; RAPID DARKENING AND BRIGHTENING RATES, DURABILITY | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-01 | — | — | US | disclosed |
| US-6146554-A | FOR PHOTOCHROMIC PLASTIC LENSES IN MASS-DYEING PROCESSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2000-11-14 | — | — | US | disclosed |
| EP-0987260-A1 | Photochromic spirofluorenopyrans | Optische Werke G. Rodenstock (DE) | 2000-03-22 | — | — | EP | disclosed |