SCHEMBL465849

SCHEMBL465849

CC1(C)CCC(CC(=O)c2ccc(-c3ccccc3)cc2)N1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HPGD P15428 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
USP2 O75604 1/20 0.43
PTPN1 P18031 1/20 0.43
GSK3B P49841 1/20 0.43
RAB9A P51151 3/20 0.42
LMNA P02545 2/20 0.42
FFAR1 O14842 1/20 0.42
CYP1A2 P05177 1/20 0.42
HIF1A Q16665 1/20 0.42
AGTR1 P30556 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764958 0.92 CYP2D6 (0.42) SMN1; SMN2MAPTL3MBTL1HPGDMMP9
SCHEMBL465837 0.77 DRD2 (0.41) MEN1KMT2A
SCHEMBL465870 0.73 KHK (0.51) SMN1; SMN2MAPTL3MBTL1HPGDALDH1A1
SCHEMBL17973390 0.69 SMN1; SMN2 (0.51) SMN1; SMN2MAPTL3MBTL1HPGDPTPN1
SCHEMBL27626012 0.66 CYP2C19 (0.40) SMN1; SMN2MAPTL3MBTL1HPGDMMP9
SCHEMBL252506 0.66 ALDH1A1 (0.51) SMN1; SMN2MAPTL3MBTL1HPGDALDH1A1
SCHEMBL6845223 0.66 ALDH1A1 (0.51) SMN1; SMN2MAPTL3MBTL1HPGDALDH1A1
SCHEMBL14178966 0.65 MAPT (0.51) SMN1; SMN2MAPTL3MBTL1HPGDALDH1A1
SCHEMBL14208954 0.65 MAPT (0.51) SMN1; SMN2MAPTL3MBTL1HPGDALDH1A1
SCHEMBL3683716 0.65 MAPT (0.51) SMN1; SMN2MAPTL3MBTL1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110268692-A1 Synergistic rodenticidal compositions BAYER CROPSCIENCE AG (DE) 2011-11-03 US disclosed
CN-102176819-A Synergistic rodenticidal agent BAYER CROPSCIENCE AG 2011-09-07 CN disclosed
EP-2343972-A1 SYNERGISTIC RODENTICIDAL AGENT Bayer CropScience AG (DE) 2011-07-20 EP disclosed
CN-101911931-A The bait system that kills mouse BAYER CROPSCIENCE AG 2010-12-15 CN disclosed
US-20100287815-A1 METHOD FOR CONTROLLING HARMFUL RODENTS IN AGRICULTURAL ENTERPRISES BAYER CROPSCIENCE AG (DE) 2010-11-18 US disclosed
WO-2010043322-A1 SYNERGISTIC RODENTICIDAL AGENT BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-04-22 WO disclosed
EP-1389039-B1 METHOD FOR CONTROLLING HARMFUL RODENTS IN AGRICULTURAL ENTERPRISES BAYER CROPSCIENCE AG (DE) 2008-11-12 EP disclosed
US-7008632-B2 Combination of biological and chemical agents to combat rodents BAYER AKTIENGESELLSCHAFT (DE) 2006-03-07 US disclosed
CN-1665389-A Deratization bait system BAYER CROPSCIENCE AG (DE) 2005-09-07 CN disclosed
US-20050181003-A1 Rodenticidal bait systems BAYER CROPSCIENCE AG (DE) 2005-08-18 US disclosed
EP-1251740-A2 COMBINATION OF BIOLOGICAL AND CHEMICAL AGENTS TO COMBAT RODENTS Bayer Aktiengesellschaft (DE) 2002-10-30 EP disclosed
WO-2001052654-A2 COMBINATION OF BIOLOGICAL AND CHEMICAL AGENTS TO COMBAT RODENTS BAYER AKTIENGESELLSCHAFT (DE) 2001-07-26 WO disclosed
US-6036970-A POISONS FOR ANIMALS SUCH AS RODENTS BAYER AKTIENGESELLSCHAFT (DE) 2000-03-14 US disclosed
EP-0719498-B1 Rodenticidal foams BAYER AG (DE) 1999-05-26 EP disclosed
EP-0789998-B1 Rodenticidal foams BAYER AG (DE) 1998-05-06 EP disclosed
EP-0789998-A1 Rodenticidal foams BAYER AG (DE) 1997-08-20 EP disclosed
EP-0784427-A1 RODENTICIDAL BAIT SYSTEMS BAYER AG (DE) 1997-07-23 EP disclosed
EP-0719498-A1 Rodenticidal foams BAYER AG (DE) 1996-07-03 EP disclosed
WO-1996009758-A1 RODENTICIDAL BAIT SYSTEMS BAYER AKTIENGESELLSCHAFT (DE) 1996-04-04 WO disclosed
US-4011332-A RODENTICIDE BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-03-08 US disclosed