Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624058 | 0.73 | ALDH1A1 (0.43) | MAPTNSD3HTR6KDM4EDRD2 | |
| SCHEMBL2982497 | 0.68 | NSD3 (0.42) | NSD3HTR6DRD2DRD4DRD3 | |
| SCHEMBL2986176 | 0.65 | DDB1 (0.54) | SLC6A4DRD2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2858713 | 0.64 | DDB1 (0.52) | SLC6A4KDM4EDRD2CYP3A4HSD17B10 | |
| SCHEMBL13999758 | 0.64 | DDB1 (0.41) | NSD3HTR6HSD17B10 | |
| SCHEMBL4608568 | 0.63 | FADS1 (0.40) | MAPTKCNH2NSD3HTR6DRD2 | |
| SCHEMBL4608571 | 0.63 | FADS1 (0.40) | MAPTKCNH2NSD3HTR6DRD2 | |
| SCHEMBL3247769 | 0.63 | DRD2 (0.48) | PLATMAPK14DRD2DRD4DRD3 | |
| SCHEMBL21811218 | 0.63 | SRC (0.40) | NSD3HTR6ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2273497 | 0.62 | DRD2 (0.64) | MAPTKCNH2NSD3HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |