Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29718684 | 1.00 | CXCL8 (0.63) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL5672222 | 1.00 | CXCL8 (0.63) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL4659044 | 1.00 | CXCL8 (0.63) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL15695552 | 0.88 | CXCL8 (0.50) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL16798960 | 0.88 | CXCL8 (0.50) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL16023820 | 0.88 | CXCL8 (0.50) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL27603271 | 0.85 | CXCL8 (0.47) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL2204495 | 0.84 | PTGS2 (0.56) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL15568192 | 0.84 | CXCL8 (0.59) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL15568736 | 0.84 | CXCL8 (0.59) | CXCL8PTGS2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987034-A | 5- ((4-chloro-2, 3-dihydro-1H-inden-1-yl) methyl) -1H-imidazole and synthetic method thereof | 安徽大学 | 2023-11-03 | — | — | CN | claimed |
| US-20160168306-A1 | NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY | WILMINGTON SAVINGS FUND SOCIETY, FSB, AS THE CURRENT COLLATERAL AGENT | 2016-06-16 | — | — | US | claimed |
| EP-1354906-B1 | Polyamide resin | MITSUBISHI GAS CHEMICAL CO (JP) | 2012-12-05 | — | — | EP | claimed |
| US-7012138-B1 | Chiral polysaccharide esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or for chiral chromatography | UNIVERSITE DE DROIT D'ECONOMIE ET DES SCIENCES D'AIZ-MARSEILLE (FR) | 2006-03-14 | — | — | US | claimed |
| US-6903119-B1 | Amino acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-07 | — | — | US | claimed |
| US-6841651-B2 | Polyamide resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-01-11 | — | — | US | claimed |
| US-20030199667-A1 | Polyamide resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-10-23 | — | — | US | claimed |
| EP-1354906-A1 | Polyamide resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-10-22 | — | — | EP | claimed |
| EP-1135417-B1 | POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY | UNIV DROIT D ECONOMIE ET DES S (FR) | 2003-06-25 | — | — | EP | claimed |
| EP-1135417-A1 | POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY | Universite De Droit, D'Economie et des Sciences D'Aix-Marseille (FR) | 2001-09-26 | — | — | EP | claimed |
| WO-2000032638-A1 | POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY | UNIVERSITE DE DROIT, D'ECONOMIE ET DES SCIENCES D'AIX-MARSEILLE (FR) | 2000-06-08 | — | — | WO | claimed |
| CN-116396257-B | Dihydrocoumarin Process for the preparation of compounds | 河南中烟工业有限责任公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2024-01-25 | — | — | US | disclosed |
| CN-116987034-A | 5- ((4-chloro-2, 3-dihydro-1H-inden-1-yl) methyl) -1H-imidazole and synthetic method thereof | 安徽大学 | 2023-11-03 | — | — | CN | disclosed |
| US-5536874-A | Process for preparing arylacetic acid and arylpropionic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0098058-B1 | SYNTHESIS OF PHENYLACETIC ACID ESTERS | ELI LILLY AND COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |
| US-4153707-A | Fungicidal isoxazolyl phenols and method of use | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4065574-A | New method for controlling fungi using 4-chromone, 4-chromanone, 4-chromone oxime and 4-chromanone oxime compounds | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | COASY, JMJD7, PTMS | CXCL8 4855/4885PTGS2 3394/4885MMP1 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.