Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660584 | 0.87 | ALDH1A1 (0.56) | HTTLMNAMAPK1ALDH1A1HPGD | |
| SCHEMBL1295410 | 0.83 | CACNA1H (0.42) | HTTLMNAMAPK1ALDH1A1HPGD | |
| SCHEMBL4660654 | 0.82 | KMT2A (0.42) | LMNARAB9AALDH1A1 | |
| SCHEMBL1036212 | 0.81 | GAA (0.68) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL4661956 | 0.80 | PPARD (0.47) | — | |
| SCHEMBL4659342 | 0.80 | MMP13 (0.48) | LMNAALDH1A1 | |
| SCHEMBL20351813 | 0.80 | HTT (0.50) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL1039522 | 0.79 | HTT (0.51) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL27685889 | 0.78 | ALOX5 (0.46) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL1979399 | 0.77 | HTT (0.53) | HTTLMNAMAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |