Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762525 | 0.88 | CA1 (0.36) | PTGDR2PRSS1TP53LMNASMN1; SMN2 | |
| SCHEMBL5156283 | 0.86 | CA1 (0.46) | PTGDR2LMNACA12CA1CA2 | |
| SCHEMBL4659575 | 0.86 | NR1H3 (0.40) | PTGDR2PRSS1TP53SMN1; SMN2THRB | |
| SCHEMBL3945673 | 0.84 | SERPINE1 (0.52) | SERPINE1POLBMAPTMEN1KMT2A | |
| SCHEMBL4761303 | 0.84 | SERPINE1 (0.46) | TP53SERPINE1LMNATHRBCA12 | |
| SCHEMBL4761420 | 0.83 | ALDH1A1 (0.39) | PTGDR2PRSS1TP53SMN1; SMN2THRB | |
| SCHEMBL4792122 | 0.83 | NAMPT (0.40) | PRSS1TP53LMNASMN1; SMN2THRB | |
| SCHEMBL4762894 | 0.81 | TP53 (0.36) | PTGDR2PRSS1TP53LMNASMN1; SMN2 | |
| SCHEMBL5151357 | 0.78 | KDM4E (0.51) | PTGDR2PRSS1CA12CA1CA2 | |
| SCHEMBL4792514 | 0.77 | MCL1 (0.41) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |