Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154936 | 0.86 | HTT (0.45) | NAMPTMEN1KMT2AHTTMAPT | |
| SCHEMBL4659575 | 0.86 | NR1H3 (0.40) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL4033646 | 0.85 | BRD4 (0.51) | NAMPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4761511 | 0.85 | BRD4 (0.44) | NAMPTMEN1KMT2AHTTMAPT | |
| SCHEMBL4762525 | 0.83 | CA1 (0.36) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL4659506 | 0.83 | PTGDR2 (0.37) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL4761420 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2AMAPTSMN1; SMN2PRSS1 | |
| SCHEMBL3943804 | 0.81 | BRD4 (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL4762894 | 0.81 | TP53 (0.36) | MEN1KMT2AHTTMAPTKDM4E | |
| SCHEMBL3942024 | 0.79 | GABRA1 (0.43) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-2001847-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107385-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |