Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857614 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TDP1 | |
| SCHEMBL1165012 | 0.82 | OPRM1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL6037285 | 0.82 | TSHR (0.33) | TDP1 | |
| SCHEMBL23707746 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL23104697 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL6736147 | 0.78 | — | — | |
| SCHEMBL598909 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL2627104 | 0.77 | — | — | |
| SCHEMBL24741005 | 0.76 | RIPK1 (0.31) | — | |
| SCHEMBL28960640 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004193-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | Merck & Co., Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007108968-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2007-09-27 | — | — | WO | disclosed |