Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287246 | 0.91 | HDAC4 (0.61) | CNR1HDAC4HDAC7HDAC5S1PR1 | |
| SCHEMBL9337191 | 0.87 | CNR1 (0.56) | CNR1HDAC4HDAC7HDAC5S1PR1 | |
| SCHEMBL465969 | 0.86 | TDP1 (0.61) | CNR1HDAC4HDAC7HDAC5CNR2 | |
| Phosphine SCHEMBL28775755 | 0.84 | TDP1 (0.58) | CNR1HDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL4505807 | 0.83 | HTT (0.56) | CNR1HDAC4HDAC7HDAC5S1PR1 | |
| SCHEMBL28419252 | 0.83 | BRD4 (0.55) | CNR1HDAC4HDAC7HDAC5S1PR1 | |
| SCHEMBL9307280 | 0.83 | L3MBTL1 (0.48) | HDAC4HDAC7HDAC5CNR2MEN1 | |
| SCHEMBL16781984 | 0.82 | L3MBTL1 (0.70) | CNR1HDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL5132036 | 0.80 | CNR1 (0.54) | CNR1HDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL467546 | 0.79 | HDAC4 (0.59) | CNR1HDAC4HDAC7HDAC5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102351675-A | Preparation process of 4-chlorophenyl benzyl ketone | UNIV CHANGZHOU | 2012-02-15 | — | — | CN | claimed |
| US-9656947-B2 | Process for creating carbon-carbon bonds using carbonyl compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2017-05-23 | — | — | US | disclosed |
| US-20150166464-A1 | PROCESS FOR CREATING CARBON-CARBON BONDS USING CARBONYL COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.) (FR) | 2015-06-18 | — | — | US | disclosed |
| CN-104661987-A | Process for creating carbon-carbon bonds using carbonyl compounds | CENTRE NAT RECH SCIENT | 2015-05-27 | — | — | CN | disclosed |
| CN-102351675-A | Preparation process of 4-chlorophenyl benzyl ketone | UNIV CHANGZHOU | 2012-02-15 | — | — | CN | disclosed |
| CN-85101497-A | Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides | — | 1986-07-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166464-A1 | PROCESS FOR CREATING CARBON-CARBON BONDS USING CARBONYL COMPOUNDS | CBR3, CBR1, CYP4F3 | CNR1 1417/4885HDAC4 2766/4885HDAC7 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.