Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659895 | 0.94 | KMT2A (0.46) | KMT2AMEN1L3MBTL1LMNASLC6A4 | |
| SCHEMBL4659897 | 0.94 | KMT2A (0.46) | KMT2AMEN1L3MBTL1LMNASLC6A4 | |
| SCHEMBL6404486 | 0.94 | KMT2A (0.46) | KMT2AMEN1L3MBTL1LMNASLC6A4 | |
| SCHEMBL4659898 | 0.86 | MEN1 (0.44) | KMT2AMEN1L3MBTL1SLC6A4ALDH1A1 | |
| SCHEMBL4663676 | 0.85 | ALDH1A1 (0.43) | LMNAALDH1A1GAA | |
| SCHEMBL4661393 | 0.85 | KMT2A (0.47) | KMT2AMEN1L3MBTL1LMNASLC6A4 | |
| SCHEMBL4661547 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1LMNAALDH1A1PTGS1 | |
| SCHEMBL4661666 | 0.84 | KMT2A (0.45) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL4660088 | 0.83 | ALDH1A1 (0.41) | LMNAALDH1A1GAA | |
| SCHEMBL4661599 | 0.81 | MEN1 (0.43) | KMT2AMEN1L3MBTL1LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |