Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661450 | 0.87 | MAPK1 (0.41) | MEN1LMNACYP3A4MAPTCYP2C9 | |
| SCHEMBL7856720 | 0.85 | MTNR1A (0.46) | KMT2ASMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL4661547 | 0.85 | ALDH1A1 (0.46) | MEN1LMNACYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL4661637 | 0.84 | CMA1 (0.42) | CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4661666 | 0.84 | KMT2A (0.45) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4816417 | 0.83 | SLC6A2 (0.43) | MEN1LMNACYP3A4MAPTCYP2C9 | |
| SCHEMBL6404486 | 0.82 | KMT2A (0.46) | MEN1LMNAKMT2ASLC6A4POLB | |
| SCHEMBL4659895 | 0.82 | KMT2A (0.46) | MEN1LMNAKMT2ASLC6A4POLB | |
| SCHEMBL4659897 | 0.82 | KMT2A (0.46) | MEN1LMNAKMT2ASLC6A4POLB | |
| SCHEMBL4663676 | 0.81 | ALDH1A1 (0.43) | LMNAMAPTCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |