Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661547 | 0.92 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL6404486 | 0.90 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL4659897 | 0.90 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL4659895 | 0.90 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL4659893 | 0.88 | MEN1 (0.42) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL4661599 | 0.84 | MEN1 (0.43) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4660099 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL4663676 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAMAPTHTT | |
| SCHEMBL4660013 | 0.80 | NPBWR1 (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL4661393 | 0.79 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |