Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662804 | 0.93 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL4661587 | 0.91 | ESR1 (0.45) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL4661453 | 0.86 | MEN1 (0.45) | MEN1KMT2AKDM4EMTNR1AMTNR1B | |
| SCHEMBL4661443 | 0.86 | ESR1 (0.50) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL5683225 | 0.86 | ESR1 (0.50) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL4660080 | 0.84 | ESR1 (0.42) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL4662613 | 0.83 | ESR1 (0.45) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL4659952 | 0.83 | ESR1 (0.45) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL4659954 | 0.83 | ESR1 (0.45) | MEN1KMT2AALDH1A1KDM4EESR1 | |
| SCHEMBL6433797 | 0.83 | ESR1 (0.45) | MEN1KMT2AALDH1A1KDM4EESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |