Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660171 | 0.93 | MEN1 (0.42) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4661587 | 0.89 | ESR1 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4661453 | 0.87 | MEN1 (0.45) | KDM4EMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4660080 | 0.85 | ESR1 (0.42) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4661396 | 0.80 | PPARG (0.38) | ALDH1A1HPGDLMNAPPARGPPARA | |
| SCHEMBL4662654 | 0.80 | PPARG (0.38) | ALDH1A1HPGDPPARGPPARA | |
| SCHEMBL4661534 | 0.80 | CMA1 (0.39) | ALDH1A1HPGDMTNR1AMTNR1BPPARG | |
| SCHEMBL4659952 | 0.80 | ESR1 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4659954 | 0.80 | ESR1 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL6433797 | 0.80 | ESR1 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |