SCHEMBL466032

SCHEMBL466032

C=CCS(=O)(=O)CCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.48
FAAH O00519 6/20 0.43
TSHR P16473 2/20 0.41
CES1 P23141 5/20 0.40
CES2 O00748 2/20 0.40
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.37
S1PR2 O95136 1/20 0.37
S1PR4 O95977 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
XBP1 P17861 1/20 0.37
S1PR1 P21453 1/20 0.37
MAPK1 P28482 1/20 0.37
AGTR1 P30556 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28917048 0.98 CA2 (0.52) CA2FAAHTSHRCES1CES2
SCHEMBL15367580 0.85 TSHR (0.42) CA2FAAHTSHRCES1CES2
SCHEMBL2985516 0.83
SCHEMBL29717 0.82 FAAH (0.43) CA2FAAHTSHRCES1CES2
P-Xylene SCHEMBL27740446 0.81 ALDH1A1 (0.40) CA2TSHRALDH1A1NPC1S1PR2
SCHEMBL196530 0.79
SCHEMBL11333906 0.78 TSHR (0.67) CA2FAAHTSHRCES1CES2
SCHEMBL11338025 0.78 TSHR (0.67) CA2FAAHTSHRCES1CES2
SCHEMBL11337949 0.78 TSHR (0.67) CA2FAAHTSHRCES1CES2
SCHEMBL11340065 0.78 TSHR (0.60) CA2FAAHTSHRCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219199-A1 MANUFACTURING METHOD FOR FP-CIT PRECURSOR, AND MANUFACTURING METHOD FOR [18F]FP-CIT USING FP-CIT PRECURSOR MANUFACTURED THEREBY (주)듀켐바이오 2023-11-16 WO claimed
CN-114249896-A Allyl-terminated aryl sulfone ether polymer and preparation method thereof 兰溪聪普新材料有限公司 2022-03-29 CN claimed
CN-110563619-B Aryl alkyl sulfone compound and reduction coupling method for constructing sulfone compound 华东师范大学 2021-07-27 CN claimed
CN-112358425-A Method for synthesizing aryl alkyl sulfone compound by oxidizing aryl alkyl thioether compound under promotion of visible light 湖南科技学院 2021-02-12 CN claimed
US-10570519-B2 Conversion coating composition comprising a dye and a method for coating a metal surface with said conversion coating composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-02-25 US claimed
CN-106281052-B Photo-curing adhesive composition 北京鼎材科技有限公司 2020-01-14 CN claimed
CN-110563619-A Aryl alkyl sulfone compound and reduction coupling method for constructing sulfone compound 华东师范大学 2019-12-13 CN claimed
CN-110521015-A ACTIVE OLED DISPLAY, METHOD FOR PREPARING ACTIVE OLED DISPLAY AND COMPOUND NOVALED GMBH 2019-11-29 CN claimed
CN-110521014-A Electronic semiconductor device and method of manufacturing electronic semiconductor device NOVALED GMBH 2019-11-29 CN claimed
CN-110462871-A Electronic semiconductor device and method for producing said electronic semiconductor device NOVALED GMBH 2019-11-15 CN claimed
CN-1058774-A PYRIDINE DERIVATIVES HAVING ANGIOTENSIN II ANTAGONISM MEIJI SEIKA CO (JP) 1992-02-19 CN claimed
CN-1057257-A The new intermediate of new imdazole derivatives and method for making thereof, gained, as the application of medicine with contain their pharmaceutical composition ROUSSEL UCLAF (FR) 1991-12-25 CN claimed
US-5015775-A Alkyl aryl sulfones and method of preparing the same ATOCHEM NORTH AMERICA, INC. (US) 1991-05-14 US claimed
EP-0337063-A1 Alkyl aryl sulfones and method of preparing the same ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1989-10-18 EP claimed
US-4833155-A SKIN DISORDERS SYNTEX (U.S.A.) INC. (US) 1989-05-23 US claimed
CN-1032788-A Novel cyclic anthranilic acid derivatives and process for preparing same KYORIN SEIYAKU KK (JP) 1989-05-10 CN claimed
CN-88102756-A Oximino ether compounds and preparation method thereof 1988-12-21 CN claimed
EP-0269981-A1 3-[alpha-(3,5-di-t-butyl-4-hydroxyphenyl)-alkanoyl]pyrroles, their de-oxy analogs, and therapeutic uses thereof SYNTEX (U.S.A.) INC. (US) 1988-06-08 EP claimed
CN-87103684-A Perhydro thia azepines and perhydro azepine derivative, the purposes in their preparation and the treatment thereof 1987-12-09 CN claimed
US-3949001-A Process for producing aryl alpha-haloalkyl sulfones SOUTHERN ILLINOIS UNIVERSITY FOUNDATION (US) 1976-04-06 US claimed