Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CPS1 | P31327 | 5/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578478 | 0.73 | MET (0.45) | MET | |
| SCHEMBL3578481 | 0.73 | MET (0.45) | MET | |
| SCHEMBL3583451 | 0.73 | MAOB (0.44) | METALOX5ALOX5APMAOBMAOA | |
| SCHEMBL3590769 | 0.73 | MAOB (0.46) | METALOX5ALOX5APMAOBMAOA | |
| SCHEMBL12993581 | 0.72 | CPS1 (0.40) | METCPS1ALOX5 | |
| SCHEMBL4662385 | 0.72 | CPS1 (0.40) | METCPS1ALOX5 | |
| SCHEMBL3586474 | 0.72 | CPS1 (0.40) | METCPS1ALOX5 | |
| Lithium Ion SCHEMBL3590770 | 0.72 | MAOB (0.42) | METTDP1ALOX5ALOX5APMAPK14 | |
| SCHEMBL24302655 | 0.65 | ALDH1A1 (0.40) | ALOX5ALOX5APMAPK14MAOBMMP13 | |
| SCHEMBL3586481 | 0.63 | MET (0.42) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805169-B1 | HISTAMINE H3 RECEPTOR INHIBITORS, THEIR PREPARATION AND THERAPEUTIC USES | LILLY CO ELI (US) | 2008-12-24 | — | — | EP | claimed |