Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159306 | 0.86 | HSD17B10 (0.52) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL4661438 | 0.78 | HTR6 (0.45) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8503692 | 0.77 | HSD17B10 (0.49) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL5786086 | 0.77 | PTGS2 (0.41) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL13908182 | 0.76 | MAPT (0.44) | MEN1MAPTKMT2AALDH1A1AGER | |
| SCHEMBL22796037 | 0.76 | MAPT (0.73) | MEN1MAPTKMT2AALDH1A1AGER | |
| SCHEMBL11307060 | 0.74 | HSD17B10 (0.46) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL5838617 | 0.74 | ADRA2C (0.55) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL3492989 | 0.73 | KDM4E (0.47) | MAPTALDH1A1KDM4EL3MBTL1CA12 | |
| SCHEMBL5544675 | 0.73 | MAPT (0.44) | MEN1MAPTKMT2AALDH1A1AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |