Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659864 | 0.95 | HDAC3 (0.41) | GAACYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL4659918 | 0.89 | PPARA (0.38) | PPARGPPARACNR1FPR2KMT2A | |
| SCHEMBL4661128 | 0.86 | HDAC3 (0.48) | GAACYP1A2CYP2D6CYP2C19PPARA | |
| SCHEMBL3674094 | 0.85 | ACACB (0.45) | PPARGPPARAL3MBTL1ACLYACACB | |
| SCHEMBL4661257 | 0.84 | MMP12 (0.40) | GAACYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL4662610 | 0.83 | MME (0.35) | GAACYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL4659891 | 0.82 | GAA (0.47) | GAACYP1A2CNR1KMT2AMEN1 | |
| SCHEMBL4659861 | 0.81 | HDAC3 (0.38) | GAACYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL4661171 | 0.81 | MME (0.37) | GAACYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL3673780 | 0.80 | HDAC3 (0.43) | CYP1A2CYP2D6CYP2C19CNR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627866-B1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7109242-B2 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1627866-A1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |