SCHEMBL4661257

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4659861	0.96	HDAC3 (0.38)	MMP12GAALTA4HPPARAPPARG
	SCHEMBL4661333	0.86	LMNA (0.39)	MMP12GAAPPARAPPARGCNR1
	SCHEMBL4662610	0.86	MME (0.35)	GAAPPARAPPARGCYP1A2CYP2D6
	SCHEMBL4661240	0.84	HTR1A (0.39)	GAAPPARAPPARGCYP1A2CYP2D6
	SCHEMBL4661128	0.82	HDAC3 (0.48)	GAAPPARACYP1A2CYP2D6CYP2C19
	SCHEMBL4659864	0.81	HDAC3 (0.41)	GAAPPARAPPARGCYP1A2CYP2D6
	SCHEMBL4661171	0.81	MME (0.37)	GAAPPARAPPARGCYP1A2CYP2D6
	SCHEMBL4661293	0.80	MMP12 (0.46)	MMP12GAALTA4HPPARAPPARG
	SCHEMBL4659918	0.78	PPARA (0.38)	PPARAPPARGCNR1FPR2KMT2A
	SCHEMBL3673780	0.76	HDAC3 (0.43)	CYP1A2CYP2D6CYP2C19CNR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.