Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661240 | 0.89 | HTR1A (0.39) | PPARAPPARGPOLBFPR2KMT2A | |
| SCHEMBL4659864 | 0.89 | HDAC3 (0.41) | PPARAPPARGFPR2KMT2AACLY | |
| SCHEMBL4661274 | 0.84 | ACACB (0.43) | PPARAPPARGACLYACACB | |
| SCHEMBL4659891 | 0.83 | GAA (0.47) | POLBKMT2APTGER2CNR1CNR2 | |
| SCHEMBL4661128 | 0.81 | HDAC3 (0.48) | PPARAPOLBFPR2ALDH1A1KMT2A | |
| SCHEMBL4662537 | 0.79 | L3MBTL1 (0.37) | POLBKMT2ACNR1CNR2 | |
| SCHEMBL28758955 | 0.78 | PPARA (0.40) | PPARAPPARGFPR2NOS2ALDH1A1 | |
| SCHEMBL4659861 | 0.78 | HDAC3 (0.38) | PPARAPPARGPOLBFPR2ALDH1A1 | |
| SCHEMBL4661257 | 0.78 | MMP12 (0.40) | PPARAPPARGPOLBFPR2ALDH1A1 | |
| SCHEMBL4661260 | 0.77 | VNN1 (0.44) | POLBALDH1A1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627866-B1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7109242-B2 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1627866-A1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
| US-20050009909-A1 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009909-A1 | Carboxylic compound and medicine comprising the same | CPT1A, GPR119, PNLIP | PPARA 68/4885PPARG 65/4885POLB 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.