Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339089 | 0.87 | TDP1 (0.45) | ALDH1A1TAAR1TSHRPTPN1KMT2A | |
| SCHEMBL4662731 | 0.82 | PTPN1 (0.34) | ALDH1A1LMNAPTPN1SLC6A2SLC6A4 | |
| SCHEMBL4661324 | 0.81 | PTPN1 (0.39) | ALDH1A1LMNATSHRL3MBTL1PTPN1 | |
| SCHEMBL4664193 | 0.80 | TYMS (0.46) | ALDH1A1L3MBTL1PTPN1SMN1; SMN2 | |
| SCHEMBL4661452 | 0.75 | CXCL8 (0.36) | ALDH1A1LMNATAAR1L3MBTL1MEN1 | |
| SCHEMBL4661305 | 0.73 | PYCR1 (0.42) | ALDH1A1LMNAPYCR1HTTTSHR | |
| SCHEMBL4661399 | 0.73 | PYCR1 (0.42) | ALDH1A1LMNAPYCR1HTTTSHR | |
| SCHEMBL4661493 | 0.73 | HTT (0.35) | LMNAHTTSLC6A4SMN1; SMN2KDM4E | |
| SCHEMBL249636 | 0.73 | PTPN1 (0.47) | ALDH1A1TAAR1TSHRPTPN1SLC6A2 | |
| SCHEMBL13197030 | 0.72 | TSHR (0.45) | ALDH1A1LMNATAAR1PYCR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |