Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339089 | 0.85 | TDP1 (0.45) | PTPN1ALDH1A1NR1H3 | |
| SCHEMBL4661308 | 0.80 | ALDH1A1 (0.39) | PTPN1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4661324 | 0.80 | PTPN1 (0.39) | PTPN1L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL4664189 | 0.76 | TYMS (0.46) | TYMSHTR6L3MBTL1HTR2AHTR2C | |
| SCHEMBL12083406 | 0.74 | ALDH1A1 (0.59) | TYMSHTR6L3MBTL1HTR2AHTR2C | |
| SCHEMBL4662731 | 0.72 | PTPN1 (0.34) | PTPN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13197030 | 0.71 | TSHR (0.45) | HTR2AALDH1A1 | |
| SCHEMBL4661438 | 0.71 | HTR6 (0.45) | HTR6L3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL9508035 | 0.71 | TYMS (0.55) | TYMSHTR6L3MBTL1CXCR4CRHBP | |
| SCHEMBL4661452 | 0.71 | CXCL8 (0.36) | L3MBTL1ALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | claimed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | claimed |
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |