Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661779 | 0.85 | RAB9A (0.37) | RAB9ANPC1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL2722735 | 0.84 | EPHX1 (0.44) | RAB9AHPGDEPHX1LMNAACHE | |
| SCHEMBL19640034 | 0.82 | EPHX1 (0.42) | RAB9ANPC1HPGDSMN1; SMN2EPHX1 | |
| SCHEMBL1536750 | 0.82 | KMT2A (0.42) | RAB9ANPC1HPGDSMN1; SMN2EPHX1 | |
| SCHEMBL4053495 | 0.80 | KMT2A (0.41) | RAB9ANPC1SMN1; SMN2EPHX1ACHE | |
| SCHEMBL526390 | 0.80 | KMT2A (0.41) | RAB9ANPC1SMN1; SMN2EPHX1ACHE | |
| SCHEMBL28742071 | 0.77 | CXCR5 (0.53) | RAB9ANPC1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL27536155 | 0.74 | LMNA (0.45) | RAB9ANPC1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL27533695 | 0.73 | CXCR5 (0.49) | RAB9ANPC1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL27569650 | 0.73 | CXCR5 (0.42) | RAB9ANPC1HPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007787-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | Novartis AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007121124-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |