SCHEMBL4661645

SCHEMBL4661645

CCOC(=O)C(=C(C)C)C(C(=O)OCC)=C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
LMNA P02545 1/20 0.52
HSD17B10 Q99714 1/20 0.52
GLO1 Q04760 1/20 0.50
MAPT P10636 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
ALOX15 P16050 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
SOAT1 P35610 1/20 0.43
TSHR P16473 2/20 0.43
EGLN1 Q9GZT9 1/20 0.41
TRPA1 O75762 1/20 0.40
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226561 0.94 ALDH1A1 (0.52) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL8323786 0.90 GLO1 (0.52) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL10886996 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL9416711 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL8327228 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL3672314 0.85 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL17827812 0.83 GLO1 (0.56) ALDH1A1LMNAHSD17B10GLO1MAPT
Butane SCHEMBL10709300 0.82 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL11156487 0.82 GLO1 (0.37) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL13990784 0.81 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10GLO1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511303-B1 MANUFACTURING METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION SAMSUNG TOTAL PETROCHEMICALS (KR) 2014-10-15 EP claimed
CN-102712705-B Preparation method of solid catalyst for propylene polymerization SAMSUNG TOTAL PETROCHEMICALS 2014-03-12 CN claimed
US-8664142-B2 Manufacturing method of solid catalyst for propylene polymerization SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2014-03-04 US claimed
US-20120264593-A1 MANUFACTURING METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2012-10-18 US claimed
EP-2511303-A2 MANUFACTURING METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION Samsung Total Petrochemicals Co. Ltd. (KR) 2012-10-17 EP claimed
US-9062135-B2 Manufacturing method of solid catalyst for propylene polymerization SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2015-06-23 US disclosed
EP-2511303-B1 MANUFACTURING METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION SAMSUNG TOTAL PETROCHEMICALS (KR) 2014-10-15 EP disclosed
CN-102712705-B Preparation method of solid catalyst for propylene polymerization SAMSUNG TOTAL PETROCHEMICALS 2014-03-12 CN disclosed
US-8664142-B2 Manufacturing method of solid catalyst for propylene polymerization SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2014-03-04 US disclosed
US-20140005038-A1 MANUFACTURING METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2014-01-02 US disclosed
US-8394734-B2 Solid catalyst for propylene polymerization and a method for preparation of polypropylene using the same SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2013-03-12 US disclosed
US-20120277389-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND A METHOD FOR PREPARATION OF POLYPROPYLENE USING THE SAME SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2012-11-01 US disclosed
US-7465821-B2 Process for preparing alkylidene-substituted-1, 4-dions derivatives BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2008-12-16 US disclosed
US-7399879-B2 Process for preparing alkylidene-substituted-1,4-dions derivatives BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2008-07-15 US disclosed
US-7399879-B2 Process for preparing alkylidene-substituted-1,4-dions derivatives BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2008-07-15 US disclosed
EP-1527039-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES Basell Poliolefine Italia S.P.A. (IT) 2005-05-04 EP disclosed
EP-1527040-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES Basel Poliolefine Italia SpA (IT) 2005-05-04 EP disclosed
US-20050080290-A1 Process for preparing alkylidene-substituted-1, 4-dions derivatives BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-04-14 US disclosed
WO-2004014838-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-02-19 WO disclosed
WO-2004014839-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES BASEL POLIOLEFINE ITALIA S.P.A. (IT) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080290-A1 Process for preparing alkylidene-substituted-1, 4-dions derivatives RTN4, NR4A2, NR3C2 ALDH1A1 845/4885LMNA 1888/4885HSD17B10 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.