Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 4/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502645 | 0.86 | PGR (0.40) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5506219 | 0.85 | PGR (0.39) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL16744210 | 0.81 | AHR (0.46) | PGRAHRCMA1EIF2AK2GAA | |
| SCHEMBL5502745 | 0.80 | PGR (0.46) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5504031 | 0.79 | ALOX15 (0.41) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5502223 | 0.79 | PGR (0.45) | PGRTDP2AHRCMA1PDK1 | |
| SCHEMBL31726677 | 0.77 | PGR (0.46) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL9832978 | 0.77 | PGR (0.46) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL4507222 | 0.77 | MAPT (0.49) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL31726573 | 0.77 | AHR (0.47) | PGRTDP2AHRCMA1EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004640-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pfizer Products Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007091147-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |