Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502223 | 0.87 | PGR (0.45) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5498169 | 0.82 | PGR (0.41) | PGRTDP2AHRCMA1CYP2D6 | |
| SCHEMBL5508737 | 0.80 | PGR (0.41) | PGRTDP2AHRCMA1CYP1A2 | |
| SCHEMBL4661785 | 0.79 | PGR (0.43) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5501521 | 0.78 | PGR (0.40) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5502645 | 0.77 | PGR (0.40) | PGRTDP2AHRCMA1CYP1A2 | |
| SCHEMBL5499443 | 0.77 | VDR (0.42) | AHRCMA1EIF2AK2GRIA1CACNG8 | |
| SCHEMBL5502745 | 0.77 | PGR (0.46) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL5506219 | 0.76 | PGR (0.39) | PGRTDP2AHRCMA1EIF2AK2 | |
| SCHEMBL4507222 | 0.74 | MAPT (0.49) | PGRTDP2AHRCMA1EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |