SCHEMBL4661828

SCHEMBL4661828

CC1CCC(C(C)C)C(CCCO)C1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 3/20 0.48
TRPA1 O75762 2/20 0.48
EPHX1 P07099 3/20 0.42
ALDH1A1 P00352 3/20 0.41
LMNA P02545 1/20 0.37
OPRM1 P35372 1/20 0.36
CYP19A1 P11511 2/20 0.35
KDM4E B2RXH2 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21380099 0.95 TRPM8 (0.47) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL3473926 0.89 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL5501057 0.87 TRPM8 (0.48) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL8688283 0.84 TRPM8 (0.46) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL28083608 0.82 OPRM1 (0.45) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL7750544 0.81 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL7747412 0.81 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL26191694 0.81 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL113450 0.81 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL26191668 0.81 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111790209-A Automobile air conditioner filter screen and interlayer preparation method thereof 张宗洲 2020-10-20 CN claimed
EP-1341512-B1 RHINOLOGICAL AGENTS SYMRISE GMBH & CO KG (DE) 2008-12-31 EP claimed
EP-1341512-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2003-09-10 EP claimed
US-6589507-B1 Foaming antacid suspension tablets DR. REGENOLD GMBH (DE) 2003-07-08 US claimed
WO-2002041861-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2002-05-30 WO claimed
CN-111790209-A Automobile air conditioner filter screen and interlayer preparation method thereof 张宗洲 2020-10-20 CN disclosed
US-20170156837-A1 DISPENSER AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION COLGATE PALMOLIVE CO (US) 2017-06-08 US disclosed
US-9610148-B2 Applicator and method for applying a tooth whitening composition COLGATE-PALMOLIVE COMPANY (US) 2017-04-04 US disclosed
US-20140356807-A1 APPLICATOR AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION COLGATE PALMOLIVE CO (US) 2014-12-04 US disclosed
US-8815216-B2 Applicator and method for applying a tooth whitening composition COLGATE-PALMOLIVE COMPANY (US) 2014-08-26 US disclosed
EP-1341512-B1 RHINOLOGICAL AGENTS SYMRISE GMBH & CO KG (DE) 2008-12-31 EP disclosed
EP-1973519-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES Symrise GmbH & Co. KG (DE) 2008-10-01 EP disclosed
EP-1686919-A1 AN APPLICATOR AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION Colgate-Palmolive Company (US) 2006-08-09 EP disclosed
CN-1245976-C Pharmaceutical formulations in hydroxypropylmenthyl cellulose capsules PHARMACIA & UPJOHN SPA (IT) 2006-03-22 CN disclosed
WO-2005037127-A1 AN APPLICATOR AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 2005-04-28 WO disclosed
WO-2005019176-A1 SUBSTITUTED AMINO-AZA-CYCLOHEXANES ACTELION PHARMACEUTICALS LTD (CH) 2005-03-03 WO disclosed
EP-1341512-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2003-09-10 EP disclosed
WO-2002041861-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2002-05-30 WO disclosed
CN-1327387-A Pharmaceutical formulations in the form of hydroxypropylmethylcellulose capsules PHARMACIA & UPJOHN SPA (IT) 2001-12-19 CN disclosed
CN-2323782-Y Constant release paster for metoprolol WANG LIXIA (CN) 1999-06-16 CN disclosed