Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661828 | 0.89 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL21380099 | 0.87 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL26191694 | 0.84 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL113450 | 0.84 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL26191668 | 0.84 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL7750544 | 0.84 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL7747412 | 0.84 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL7610579 | 0.82 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL5501057 | 0.82 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL28523754 | 0.81 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014273-A1 | Use of methyl methyl ether and another ether to provide a feeling of cleanliness and purity | Symrise GmbH & Co. KG (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-1341512-B1 | RHINOLOGICAL AGENTS | SYMRISE GMBH & CO KG (DE) | 2008-12-31 | — | — | EP | claimed |
| EP-1341512-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002041861-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2002-05-30 | — | — | WO | claimed |
| CN-117481998-A | Retinol substitutes in skin treatment | 西姆莱斯有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-9445606-B2 | Use of 4-hydroxydihydrochalcones and their salts for enhancing an impression of sweetness | SYMRISE AG (DE) | 2016-09-20 | — | — | US | disclosed |
| US-8574554-B2 | Uses of 4-methyl-5-hydroxy-hexanoic acid lactone | SYMRISE AG (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20100233102-A1 | USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS | SYMRISE GMBH & CO. KG (DE) | 2010-09-16 | — | — | US | disclosed |
| EP-2014273-A1 | Use of methyl methyl ether and another ether to provide a feeling of cleanliness and purity | Symrise GmbH & Co. KG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-1341512-B1 | RHINOLOGICAL AGENTS | SYMRISE GMBH & CO KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | SYMRISE GMBH & CO. KG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080220140-A1 | USE OF PROPENYLPHENYL GLYCOSIDES FOR ENHANCING SWEET SENSORY IMPRESSIONS | SYMRISE GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20070297993-A1 | Novel Use of Nonenolide | SYMRISE GMBH & CO. KG (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1868561-A1 | MENTHOL-CONTAINING SOLIDS COMPOSITION | Symrise GmbH & Co. KG (DE) | 2007-12-26 | — | — | EP | disclosed |
| US-20070254826-A1 | Novel uses of 4-methyl-5-hydroxy-hexanoic acid lactone | SYMRISE GMBH & CO. KG (DE) | 2007-11-01 | — | — | US | disclosed |
| EP-1793797-A1 | USE OF EUGENOL ACETATE AS AN AGENT AGAINST BAD BREATH | Symrise GmbH & Co. KG (DE) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006106130-A1 | MENTHOL-CONTAINING SOLIDS COMPOSITION | SYMRISE GMBH & CO. KG (DE) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006032666-A1 | USE OF EUGENOL ACETATE AS AN AGENT AGAINST BAD BREATH | SYMRISE GMBH & CO. KG (DE) | 2006-03-30 | — | — | WO | disclosed |
| EP-1341512-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002041861-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | TAS2R5, TAS2R20, TAS2R40 | TRPM8 266/4885TRPA1 343/4885EPHX1 650/4885 |
| US-20070297993-A1 | Novel Use of Nonenolide | TAS2R14, TAS2R4, TAS2R7 | TRPM8 561/4885TRPA1 137/4885EPHX1 1090/4885 |
| US-20100233102-A1 | USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS | TAS2R4, TAS2R1, TAS2R20 | TRPM8 687/4885TRPA1 540/4885EPHX1 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.