Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NGFR | P08138 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938839 | 0.84 | ALDH1A1 (0.41) | KDM4EHSD17B10ALDH1A1LMNANGFR | |
| SCHEMBL14356133 | 0.84 | KIF11 (0.43) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL29619548 | 0.80 | PIM1 (0.49) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL3490960 | 0.80 | PIM1 (0.49) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL24189567 | 0.79 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1LMNANGFR | |
| SCHEMBL4815012 | 0.78 | HSD17B10 (0.59) | KDM4EHSD17B10ALDH1A1LMNANGFR | |
| SCHEMBL3601642 | 0.74 | HSD17B10 (1.00) | KDM4EHSD17B10ALDH1A1LMNANGFR | |
| SCHEMBL6838149 | 0.73 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1LMNANGFR | |
| SCHEMBL4810186 | 0.72 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1LMNANGFR | |
| SCHEMBL3107966 | 0.71 | ALDH1A1 (0.54) | KDM4EHSD17B10ALDH1A1LMNANGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-106460053-A | MIRNA expression profiling in thyroid tumor classification | 罗塞塔金诺米克斯有限公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-0819133-B1 | COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES | EPOCH BIOSCIENCES INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1224332-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | Epoch Biosciences, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001031063-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | EPOCH BIOSCIENCES, INC. (US) | 2001-05-03 | — | — | WO | disclosed |